IIT Delhi researchers develop scar-tissue model for screening drugs

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Researchers at the Indian Institute of Technology (IIT) Delhi have for the first time developed a 3D scar-tissue model through tissue engineering. The two-member team led by Prof. Sourabh Ghosh from the Department of Textile Technology at IIT Delhi was successful in replicating the early inflammatory microenvironment that initiates a cascade of events that lead to scar development. The team replicated all the five features and two signalling pathways that form scar tissue. Creating scar tissue in the lab has great implications for the pharmaceutical industry. “The cosmetic and pharmaceutical industries, which are developing anti-fibrosis or anti-scar medicines, need not have to test them on animals.